Explore Psilocybin Safely & Responsibly
This article is intended to offer information that supports your awareness around the safety and responsible exploration of psilocybin.
When approaching psychedelics and plant medicines, the first and most essential principle is simple: safety first. These substances are powerful allies, not shortcuts. As you engage with them, you are entering a relationship—one that asks for humility, preparation, and respect. Understanding dosage is a core component of harm reduction, and a foundation for meaningful experiences. In this guide, we’ll explore how to approach magic mushroom dosing across different intentions and use cases, assuming you have legal access to psilocybin.
If you’re new to magic mushrooms, it’s important to recognize that not all psilocybin-containing mushrooms are the same. Different species—and even different strains—carry varying levels of potency and personality. There are also multiple ways to dose mushrooms, each offering a different level of engagement with the mushroom consciousness. From microdoses that gently shift mood and clarity, to “heroic doses” that dismantle the ego and reveal the deeper self, each path opens a very different doorway. The right approach is always guided by intention: Why am I here? What am I seeking?
Even within shared dosage frameworks, potency is nuanced. Freshness, preparation, storage, the state of your nervous system, prior experience, and your emotional readiness all shape the experience. This isn’t just chemistry—it’s communion. Psilocybin works with your psychology, your history, your environment, and your body.
The intensity of your psilocybin mushroom experience relies on the following factors:
Type of mushroom
Dosage amount
How long ago the mushrooms were harvested
Raw versus Dried
Mushroom preparation
Mushroom storage
Individual differences (e.g., metabolism, serotonin receptor numbers, psychedelic experience)
Medications (current or recent discontinuation), drugs or alcohol
Your state of mind
Type and amount of food as well as when you last ate
The Right Tools for Proper Dosing
Unless you’re buying pre-made, pre-measured psilocybin-containing products, such as magic mushroom chocolate bars, or capsules, you’ll need to get yourself a micro digital scale. This will help you accurately weigh your dose. Consider your dose seriously, whether you’re microdosing or macrodosing. And always ensure you’re ingesting the right amount of mushrooms to help generate the desired effect.
Keep in mind that the weight of the dose will depend on whether the mushrooms are wet or dried. Wet mushrooms have more water weight than dried mushrooms.
Let’s Start Small – Microdose
Microdosing involves consuming small, non-perceptual amounts of psilocybin-containing mushrooms. This means that you don’t feel or perceive any of the mind-altering effects of the mushroom. You may feel subtle effects like a boost in mood or energy. These dosing protocols typically contain 100 mg to 250 mg of dried magic mushrooms (5-10% of a standard dose) consumed across dosing days and days off. There are six microdosing protocols that are most common. Of these, the Stamets Protocol (5 days in a row microdosing, then 2 days off, repeat) and the Fadiman Protocol (1 day microdosing, then 2 days off, repeat) are the most prolific. Remember: if you feel any psychedelic effects, it’s not a microdose, and you should dial back your dosage.
Mushroom Doses for Mingling
Much of the media attention that has shined on our magical fungi friends is focused on the therapeutic benefits of psilocybin. Mushrooms are being used to help those suffering from mental health challenges such as depression, anxiety, and substance use disorders. However, it’s important to note that research from self-reports shows microdosing and small perceptual doses can be helpful in easing social anxiety, enabling deep, relaxed states, and helping people focus.
Exploring Social Dosing and Low Doses
Not much is said about what I like to call ‘social dosing’ with magic mushrooms. Current trends indicate a major movement away from alcohol. More people are exploring alternatives to that bottle of wine on a Friday night. Instead, they are looking to plant medicine or mocktails as an alternative to helping them decompress, socialize, and celebrate.
If you have limited or no experience with psilocybin or plant medicines in general, it’s wise to follow the golden rule of “start low, go slow.” Using psychedelics intentionally and productively is about forming a relationship with the molecule or consciousness of the plant or fungi. The sound practice of warming up to the experience out of the gate enables you to get used to the non-ordinary state of consciousness. It allows you to breathe into the novelty and strangeness of the experience.
Delve into The Wonderful and Diverse World of Psilocybin Mushroom Strains.
So, what does this social or low dose look like? For your run-of-the-mill cubensis strain, like Golden Teacher or Penis Envy, 0.5 grams to 1.0 grams of dried mushrooms is a good start. This will have you feeling the mushiness of the mushroom. A medium dose of 2.0 to 3.0 grams is where you will most likely feel psychedelic effects but may still be able to walk around and maintain a sense of who you are. But as already mentioned, other factors will play into how strong or intense the experience feels. Start your exploration of this use case slowly, and do it on familiar ground around people with whom you’re comfortable. Or try it on your own to feel it out on a practice run before embarking out into the world and partaking in psilocybin with others in social situations.
Dosing for Lift Off
Dried mushrooms taken at doses between 2.5 grams to 5 grams will induce classic psychedelic experiences with kaleidoscope visuals when eyes are closed or open, sensory and perceptual changes, synesthesia (like hearing colors or tasting sounds), cognitive changes, and ego dissolution. A ‘heroic dose’, as coined by Terrence McKenna, describes doses over 5 grams of dried mushrooms (or roughly 50 mg of psilocybin). As the name implies, this huge dose may cause a complete loss of the sense of self (known as “ego dissolution” or “ego death”) and the ability to think or make decisions. This level of cognitive impairment should not be taken lightly; careful preparation and supervision are necessary for safety.
Whatever the dose of mushrooms, know that every individual is unique, and each psychedelic experience is different. The dose is only one factor in how strong the effects will feel.
Get the Specs of the Mushroom Species
Wherever you’re getting mushrooms from, make sure it’s a trusted source and know what species you’re getting. As previously mentioned, magic mushroom potency does vary by species. Some mushroom varieties, like the Enigma strain, are known to be 1.5x to 2x stronger than other cubensis strains.
Mushrooms can be contaminated with molds or bacteria. If consumed, they may cause nausea or vomiting. The similarity between certain types of mushrooms can lead to mix-ups, which could prove fatal.
Synthetic Psilocybin Doses in Research
For research studies, a synthetic or extracted version of psilocybin is typically used. The psilocybin molecule is produced in a laboratory, meaning no mushrooms are needed. Extraction methods isolate psilocybin from mushrooms. Pure psilocybin in capsules allows researchers to administer a precise and consistent dose to all clinical trial participants. Since they are not using dried mushrooms, the dosage is given as milligrams of synthetic psilocybin. Some studies even take into account a person’s body weight and give doses as mg of psilocybin/kg of body weight or as mg of psilocybin/70kg (the average human weight), but at least one study did not find differences in how people felt when doses were adjusted for body weight.
Here are example doses of psilocybin (note: not dried magic mushrooms) given in research studies. Most people will notice some small perceptual shifts after taking 2-4 mg of psilocybin. Psychoactive effects are experienced after ingesting 8-20 mg, with the majority of people reporting mystical experiences at a dose of 20 mg or higher.
10 mg psilocybin – low dose
20-30 mg psilocybin – medium or standard dose
30-40 mg psilocybin – high dose
>40 mg psilocybin – very high dose
Synthetic or Extracted Psilocybin vs Mushroom Dosage
You may be wondering how extracted or synthetic psilocybin doses compare to dried mushrooms. As a comparison for dosage, there is typically 1% psilocybin per 1 gram of dried Psilocybe cubensis mushrooms. For example, 3.5 grams (equivalent to an eighth ounce) of dried Psilocybe cubensis is likely to contain 35 mg of psilocybin (high dose), and 2.0 grams of dried mushrooms contain 20 mg of psilocybin (standard dose). Keep in mind that psilocybin levels in dried mushrooms can vary quite a bit between species, ranging from 0.1% to 2% of dry weight. Mushroom caps usually have higher psilocybin levels than mushroom stems.
Set and Setting
Although not dose-specific, your environment and state of mind play a big role in the effects of psychedelic fungi. Choosing a comfortable, familiar, and set and setting can have a significantly positive impact on your experience. Avoid using magic mushrooms if you are in a negative or stressful mindset. Stay away from media such as violent video games, news, pornography, and even social media for a day or more before consuming magic mushrooms.
Whatever your dose, set your intentions and thank the Universe for the gifts in your life and all the experiences that have led you to this very moment.
Body Weight & Metabolism
Generally speaking, it’s believed that people with higher body weight may require a slightly higher dosage to achieve the desired effects. However, there isn’t a ton of evidence to support this. Weight should not be the sole factor in determining your dose.
More importantly, personal metabolism and susceptibility to mind-altering substances play a larger role in determining dose. If you feel loopy after one alcoholic beverage or a puff of cannabis, you should dose on the light side. Remember to start low and go slow.
Tolerance
Repeated psilocybin use over periods of time does build tolerance. This means that over time, you may need a slightly higher dose to achieve the same effects. Tolerance to psilocybin builds rather rapidly and diminishes quickly after use. When consuming magic mushrooms, it’s a common practice to assess your experience at the 60 to 90-minute mark (note the time when you take a dose). You can then determine if you’d like to consume a bit more of the fungus to produce more noticeable effects.
After this additional dose window of 60-90 minutes, your tolerance will build to any additional psilocybin introduced into your system.
Follow Best Practices
Stay hydrated and avoid alcoholic beverages and other substances or medications that may interact negatively with Psilocybin. If you’re not experienced with psychedelics, it’s highly advisable to have a sober and trusted friend with you. A psychedelic facilitator or “trip sitter” can help ensure your safety and comfort.
If you’re working on ways to improve your human experience and need help, a trusted therapist and licensed practitioner who has experience working with psilocybin integration can be incredibly productive and rewarding. Community Groups are another great option for integration support.